The England midfielder is yet to play a game for the Gunners this season, having suffered a broken leg in August.
But according to the Daily Star, Wilshere will get his first taste of competitive football by turning out for Arsenal’s Under-21s against Newcastle on Friday night (7pm).
Wilshere tweeted on April 1 to his followers that he had returned to training, as he looks to stake a late bid to be included in Roy Hodgson’s England squad.
The 24-year-old is still in contention for a place on the plane to France, but he will need a successful run of games if Hodgson is to seriously consider him.
Wilshere was making headlines earlier this week for the wrong reasons after reports emerged of him allegedly being involved in a fracas at a London Nightclub.
The midfielder strongly denies any involvement in the altercation, but photos of him talking with police prompted Wenger to call him in for meeting.
Jack Wilshere - Spotlight On
A successful run out for Arsenal’s reserves could see him involved in the the club’s run-in for the title in the final few games of the season.
The Gunners sit third in the table, 11 points off leaders Leicester.