The star’s possessions raised more than £4million in total.
The script, which sold for seven times its pre-sale estimate, was one of more than 200 personal treasures to go on sale at London auction house Christie’s.
Hepburn, who played socialite Holly Golightly in the f lm version of Truman Capote’s novella, died in 1993 from cancer, aged 63.
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As well as the 1961 film script, which featured her handwritten notes and deleted scenes, Hepburn’s working script from the 1963 fi lm My Fair Lady sold for £206,250.
An engraved Tiffany bangle, given to her by director Steven Spielberg, fetched £332,750.
Audrey Hepburn & William Holden - In the Moonlight
But it was the style icon’s blue satin sleep mask with blue lacetrimmed flowers which attracted the most attention.
With the highest number of bidders for any lot, it sold for £6,250 – 50 times its pre-sale estimate.
The auction drew bidders from 46 countries across six continents.
More of the actress’s clothes, shoes and jewellery are being auctioned online.