Niree Johnstone was seriously injured when the Vauxhall Corsa she was travelling in collided with a BMW 120.
The little girl from Paisley, Renfrewshire, was taken to the Queen Elizabeth University Hospital in Glasgow but later died of her injuries.
Related articles
The Corsa was being driven on Tuesday at around 4.50pm in Paisley's Gleniffer Road by a 20-year-old woman who was taken to the same hospital with serious injuries. She is described as being in a stable condition.
A three-year-old boy, who was a passenger in the car, was taken in for observation but has since been released and a 24-year-old man, the front-seat passenger, was uninjured.
Police Scotland said the 34-year-old man who was driving the BMW was also uninjured.
This was a serious road crash which has resulted in the death of a young girl
The road was closed for six hours as crash investigators conducted an examination.
Sergeant Kenneth Malaney, from Police Scotland, said: "This was a serious road crash which has resulted in the death of a young girl. Road policing officers are continuing to investigate.
"I would ask that anyone who witnessed the collision to please get in contact with any information you may have."